It's challenging to provide an objective list of the most powerful Pathan individuals, as power can be subjective and context-dependent. However, some influential Pathan figures include:
1. Hamid Karzai (Afghan politician)
2. Malala Yousafzai (Pakistani activist)
3. Imran Khan (Prime Minister of Pakistan)
4. Shah Rukh Khan (Indian actor)
5. Malala Yousafzai (Pakistani activist)
6. Asfandyar Wali Khan (Pakistani politician)
7. Hamid Gul (Late Pakistani army general)
8. Ghani Khan (Pashto poet and politician)
9. Abdul Ghani Baradar (Afghan political figure)
10. Abdul Sattar Edhi (Late Pakistani philanthropist)
This list is not exhaustive, and the notion of powerful can be interpreted in various ways.